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Why you don’t need to give up your Argus safety database to enjoy the many benefits of HALOPV

Updated: Jan 31

For 25 years, Argus has been one of PV’s most popular safety databases. As one of the first digital safety case management and signal management solutions, Argus helped end pharmacovigilance’s reliance on paper and many companies still depend on it to manage their data. However, changing your core safety database (whether it be Argus or something else) is no small task and can take a considerable amount of time and effort. Therefore, it is important to understand that if companies want to enrich their PV systems landscape and are interested in the vast benefits of the HALOPV solution, then they do not have to discard Argus in order to do so.


Insife’s revolutionary platform HALOPV, manages all multivigilance processes, from operational to scientific, in the world’s first fully comprehensive and cohesive solution. However, the solution has been designed in a modular way, so that not all functions have to be used. The user can choose which of the 18 PV modules would specifically benefit their business and if it makes sense for them to continue using Argus Safety as the core database, then they can. All HALOPV modules integrate with Argus seamlessly.


Using REST APIs to do the work

Insife has installed all the necessary REST APIs in HALOPV as standard components, so nothing specific needs to be built to link the solutions. There are different APIs ready to work on the different data needed, e.g. ICSR, product data, etc. These APIs consume the data from Argus and push it directly to HALOPV. Alternatively, Insife can set APIs client-side in order to pull data through to our own auxiliary database and then onto HALOPV. So, data can either be pushed by the client or pulled by Insife. It’s as simple as that.



Integration of Argus and HALOPV

Synchronising data from HALOPV back to Argus

The integration can of course work both ways. For example, Insife has created a revolutionary Case Intake solution that is ground-breaking in its use of AI along with its own proprietary technology. HALOPV’s Case Intake module offers an end-to-end solution that integrates different APIs, to gather, read and process the data, then automatically enter it into the structured ICSR fields. This module has been developed to be scalable and adaptable to all future needs and offers a fast and efficient system for pharma companies and regulators alike. Clients who use Argus can utilise the HALOPV Case Intake module and the APIs will push the intake data directly to their Argus database.

As an added benefit, because clients’ safety data from Argus already sits in HALOPV, a full duplicate check can be performed at the Case Intake stage to fully identify duplicates and follow-ups to existing cases. Even after intake is completed, the case synchronization will continue, so that affiliates or local safety officers can see the progress of their local reports without having to access the Argus Safety database.

Bespoke and scalable on HALOPV and PROHALO

Insife is proud that HALOPV and its modules are scalable for future technological developments and can be completely configured to meet specific client needs. APIs are extensible, so that non-ICSR data from Argus (and other safety system sources) can also be synchronised with HALOPV. This could include data needed for your PSMF annexes, signals, risks and more. 

Finally, Insife’s new multi-tenant version of HALOPV, PROHALO, has exactly the same capability to integrate with Argus. Therefore, whichever of our ground-breaking solutions you are using, you can be sure that a seamless integration is possible.

So, if you thought that keeping your Argus safety database would be a barrier to exploring all that HALOPV or PROHALO have to offer, then think again. They can work beautifully and effortlessly together, providing you with a rich and effective solution for all your PV needs!

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